AARS2 (aa478-489) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q5JTZ9 |
Other Accession | NP_065796.1, 57505 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 107340 Da |
Gene ID | 57505 |
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Other Names | Alanine--tRNA ligase, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03133}, 6.1.1.7 {ECO:0000255|HAMAP-Rule:MF_03133}, Alanyl-tRNA synthetase {ECO:0000255|HAMAP-Rule:MF_03133}, AlaRS {ECO:0000255|HAMAP-Rule:MF_03133}, AARS2 {ECO:0000255|HAMAP-Rule:MF_03133} |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | AARS2 (aa478-489) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AARS2 {ECO:0000255|HAMAP-Rule:MF_03133} |
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Synonyms | AARSL, KIAA1270 |
Function | Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain. |
Cellular Location | Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03133, ECO:0000269|PubMed:21549344} |
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Provided below are standard protocols that you may find useful for product applications.
References
Toward the full set of human mitochondrial aminoacyl-tRNA synthetases: characterization of AspRS and TyrRS. Bonnefond L, Fender A, Rudinger-Thirion J, Giegé R, Florentz C, Sissler M. Biochemistry. 2005 Mar 29;44(12):4805-16. PMID: 15779907
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