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TSPYL2 (aa441-454) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - TSPYL2 (aa441-454) Antibody (internal region) AF3688a
    AF3688a (0.3 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q9H2G4
Other Accession NP_071400.1, 64061
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 79435 Da
Additional Information
Gene ID 64061
Other Names Testis-specific Y-encoded-like protein 2, TSPY-like protein 2, Cell division autoantigen 1, Cutaneous T-cell lymphoma-associated antigen se20-4, CTCL-associated antigen se20-4, Differentially-expressed nucleolar TGF-beta1 target protein, Nuclear protein of 79 kDa, NP79, TSPYL2, CDA1, DENTT, TSPX
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTSPYL2 (aa441-454) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSPYL2
Synonyms CDA1, DENTT, TSPX
Function Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression.
Cellular Location Nucleus. Cytoplasm. Note=Enriched in transcriptionally active regions of chromatin in neurons
Tissue Location Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas
Research Areas
Citations (0)
citation

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References

Role of the Y-located putative gonadoblastoma gene in human spermatogenesis. Lau YF, Li Y, Kido T. Syst Biol Reprod Med. 2011 Feb;57(1-2):27-34. PMID: 21204751

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$ 341.00
Cat# AF3688a
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