TSPYL2 (aa2-13) Antibody (N-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q9H2G4 |
Other Accession | NP_071400.1, 64061 |
Predicted | Human, Mouse, Rat, Pig |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 79435 Da |
Gene ID | 64061 |
---|---|
Other Names | Testis-specific Y-encoded-like protein 2, TSPY-like protein 2, Cell division autoantigen 1, Cutaneous T-cell lymphoma-associated antigen se20-4, CTCL-associated antigen se20-4, Differentially-expressed nucleolar TGF-beta1 target protein, Nuclear protein of 79 kDa, NP79, TSPYL2, CDA1, DENTT, TSPX |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | TSPYL2 (aa2-13) Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TSPYL2 |
---|---|
Synonyms | CDA1, DENTT, TSPX |
Function | Part of the CASK/TBR1/TSPYL2 transcriptional complex which modulates gene expression in response to neuronal synaptic activity, probably by facilitating nucleosome assembly. May inhibit cell proliferation by inducing p53-dependent CDKN1A expression. |
Cellular Location | Nucleus. Cytoplasm. Note=Enriched in transcriptionally active regions of chromatin in neurons |
Tissue Location | Ubiquitously expressed, with highest levels in brain, testis and heart, and lowest levels in liver and pancreas |
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Provided below are standard protocols that you may find useful for product applications.
References
Role of the Y-located putative gonadoblastoma gene in human spermatogenesis. Lau YF, Li Y, Kido T. Syst Biol Reprod Med. 2011 Feb;57(1-2):27-34. PMID: 21204751
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