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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > SOX11 (aa309-323) Antibody (internal region)
SOX11 (aa309-323) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | P35716 |
| Other Accession | NP_003099.1, 6664, 20666 (mouse), 84046 (rat) |
| Reactivity | Human |
| Predicted | Mouse, Rat, Pig |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 46679 Da |
| Gene ID | 6664 |
|---|---|
| Other Names | Transcription factor SOX-11, SOX11 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | SOX11 (aa309-323) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | SOX11 |
|---|---|
| Function | Transcription factor that acts as a transcriptional activator (PubMed:24886874, PubMed:26543203). Binds cooperatively with POU3F2/BRN2 or POU3F1/OCT6 to gene promoters, which enhances transcriptional activation (By similarity). Acts as a transcriptional activator of TEAD2 by binding to its gene promoter and first intron (By similarity). Plays a redundant role with SOX4 and SOX12 in cell survival of developing tissues such as the neural tube, branchial arches and somites, thereby contributing to organogenesis (By similarity). |
| Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00267, ECO:0000269|PubMed:24886874, ECO:0000269|PubMed:35938035} |
| Tissue Location | Expressed primarily in the brain and heart, with low expression in the kidney, pancreas and muscle |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
SOX11 expression in mantle cell lymphoma. Xu W, Li JY. Leuk Lymphoma. 2010 Nov;51(11):1962-7. PMID: 20919851
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$ 423.00
Cat# AF3673a
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