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IRF2BP1 (aa461-474) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q8IU81 |
| Other Accession | NP_056464.1, 26145 |
| Reactivity | Human, Mouse, Rat |
| Predicted | Pig, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 61688 Da |
| Gene ID | 26145 |
|---|---|
| Other Names | Interferon regulatory factor 2-binding protein 1, IRF-2-binding protein 1, IRF-2BP1, Probable E3 ubiquitin-protein ligase IRF2BP1, 6.3.2.-, IRF2BP1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | IRF2BP1 (aa461-474) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | IRF2BP1 |
|---|---|
| Function | Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. |
| Cellular Location | Nucleus. |
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Provided below are standard protocols that you may find useful for product applications.
References
IRF2-binding protein-1 is a JDP2 ubiquitin ligase and an inhibitor of ATF2-dependent transcription. Kimura M, FEBS letters 2008 Aug 582 (19): 2833-7. PMID: 18671972
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