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TH1L Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - TH1L Antibody (internal region) AF3380a
    AF3380a (0.5 µg/ml) staining of nuclear Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q8IXH7
Other Accession NP_945327.1, 51497, 57314 (mouse)
Reactivity Human
Predicted Mouse, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 66247 Da
Additional Information
Gene ID 51497
Other Names Negative elongation factor C/D, NELF-C/D, TH1-like protein, NELFCD, NELFD, TH1, TH1L
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTH1L Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name NELFCD
Synonyms NELFD, TH1, TH1L
Function Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II (PubMed:12612062). The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex (PubMed:10199401).
Cellular Location Nucleus.
Tissue Location Widely expressed. Expressed in heart, brain, lung, placenta, liver, skeletal and cardiac muscle, adrenal, thyroid, kidney and pancreas.
Research Areas
Citations (0)
citation

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References

Trihydrophobin 1 attenuates androgen signal transduction through promoting androgen receptor degradation. Yang Y, Zou W, Kong X, Wang H, Zong H, Jiang J, Wang Y, Hong Y, Chi Y, Xie J, Gu J, Journal of cellular biochemistry 2010 Apr 109 (5): 1013-24. PMID: 20069563

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$ 341.00
Cat# AF3380a
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Availability: 7-10 days
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