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ALDH5A1 (aa 485-496) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - ALDH5A1 (aa 485-496) Antibody (internal region) AF3359a
    AF3359a (0.5 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • IHC - ALDH5A1 (aa 485-496) Antibody (internal region) AF3359a
    AF3359a (5 µg/ml) staining of paraffin embedded Human Liver. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, E
Primary Accession P51649
Other Accession NP_733936.1, NP_001071.1, 7915, 214579 (mouse), 291133 (rat)
Reactivity Human, Mouse, Rat
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 57215 Da
Additional Information
Gene ID 7915
Other Names Succinate-semialdehyde dehydrogenase, mitochondrial, 1.2.1.24, Aldehyde dehydrogenase family 5 member A1, NAD(+)-dependent succinic semialdehyde dehydrogenase, ALDH5A1, SSADH
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsALDH5A1 (aa 485-496) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ALDH5A1 (HGNC:408)
Synonyms SSADH
Function Catalyzes one step in the degradation of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).
Cellular Location Mitochondrion.
Tissue Location Brain, pancreas, heart, liver, skeletal muscle and kidney. Lower in placenta
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognize both reported isoforms (NP_733936.1; NP_001071.1). Amino acid numbering in name calculated from NP_733936.1.

References

Human variation in alcohol response is influenced by variation in neuronal signaling genes. Joslyn G, Ravindranathan A, Brush G, Schuckit M, White RL, Alcoholism, clinical and experimental research 2010 May 34 (5): 800-12. PMID: 20201926

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$ 341.00
Cat# AF3359a
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Availability: 7-10 days
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