NDUFS8 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | O00217 |
Other Accession | NP_002487.1, 4728, 225887 (mouse), 293652 (rat) |
Reactivity | Mouse, Rat |
Predicted | Human, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 23705 Da |
Gene ID | 4728 |
---|---|
Other Names | NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial, 1.6.5.3, 1.6.99.3, Complex I-23kD, CI-23kD, NADH-ubiquinone oxidoreductase 23 kDa subunit, TYKY subunit, NDUFS8 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NDUFS8 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NDUFS8 |
---|---|
Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:22499348). Essential for the catalytic activity and assembly of complex I (PubMed:22499348). |
Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:P42028}; Matrix side {ECO:0000250|UniProtKB:P42028} |
Tissue Location | Expressed in all tissues with the highest level in heart and skeletal muscle and the lowest level in lung |
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Provided below are standard protocols that you may find useful for product applications.
References
Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, Kawamoto M, Kamatani N, Journal of human genetics 2009 Jun 54 (6): 317-23. PMID: 19343046
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