NDUFS1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P28331 |
Other Accession | NP_004997.4, 4719, 227197 (mouse), 301458 (rat) |
Reactivity | Human, Mouse |
Predicted | Rat, Rabbit, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 79468 Da |
Gene ID | 4719 |
---|---|
Other Names | NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial, 1.6.5.3, 1.6.99.3, Complex I-75kD, CI-75kD, NDUFS1 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | NDUFS1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | NDUFS1 |
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Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:30879903, PubMed:31557978). Essential for catalysing the entry and efficient transfer of electrons within complex I (PubMed:31557978). Plays a key role in the assembly and stability of complex I and participates in the association of complex I with ubiquinol-cytochrome reductase complex (Complex III) to form supercomplexes (PubMed:30879903, PubMed:31557978). |
Cellular Location | Mitochondrion inner membrane; Peripheral membrane protein {ECO:0000250|UniProtKB:P15690}; Matrix side {ECO:0000250|UniProtKB:P15690} |
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Provided below are standard protocols that you may find useful for product applications.
References
Association study between single-nucleotide polymorphisms in 199 drug-related genes and commonly measured quantitative traits of 752 healthy Japanese subjects. Saito A, Kawamoto M, Kamatani N, Journal of human genetics 2009 Jun 54 (6): 317-23. PMID: 19343046
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