ALDH9A1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, E |
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Primary Accession | P49189 |
Other Accession | NP_000687.3, 223 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 53802 Da |
Gene ID | 223 |
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Other Names | 4-trimethylaminobutyraldehyde dehydrogenase, TMABADH, 1.2.1.47, Aldehyde dehydrogenase E3 isozyme, Aldehyde dehydrogenase family 9 member A1, 1.2.1.3, Gamma-aminobutyraldehyde dehydrogenase, 1.2.1.19, R-aminobutyraldehyde dehydrogenase, ALDH9A1, ALDH4, ALDH7, ALDH9 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ALDH9A1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ALDH9A1 |
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Synonyms | ALDH4, ALDH7, ALDH9 {ECO:0000303|PubMed: |
Function | Converts gamma-trimethylaminobutyraldehyde into gamma- butyrobetaine with high efficiency (in vitro). Can catalyze the irreversible oxidation of a broad range of aldehydes to the corresponding acids in an NAD-dependent reaction, but with low efficiency. Catalyzes the oxidation of aldehydes arising from biogenic amines and polyamines. |
Cellular Location | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9JLJ3}. Cytoplasm |
Tissue Location | Detected in brain (at protein level) (PubMed:8645224). High expression in adult liver, skeletal muscle, and kidney. Low levels in heart, pancreas, lung and brain (PubMed:8786138) Expressed in all regions of the brain. Expression levels are variable in the different brain areas, with the highest levels in the spinal cord and the lowest in the occipital pole. |
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Provided below are standard protocols that you may find useful for product applications.
References
Aldehyde dehydrogenase from adult human brain that dehydrogenates gamma-aminobutyraldehyde: purification, characterization, cloning and distribution. Kikonyogo A, Pietruszko R, The Biochemical journal 1996 May 316 ( Pt 1) : 317-24. PMID: 8645224
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