ALDH3A1 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, E |
---|---|
Primary Accession | P30838 |
Other Accession | NP_000682.3, 218 |
Reactivity | Human, Mouse |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 50395 Da |
Gene ID | 218 |
---|---|
Other Names | Aldehyde dehydrogenase, dimeric NADP-preferring, 1.2.1.5, ALDHIII, Aldehyde dehydrogenase 3, Aldehyde dehydrogenase family 3 member A1, ALDH3A1, ALDH3 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | ALDH3A1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ALDH3A1 |
---|---|
Synonyms | ALDH3 |
Function | ALDHs play a major role in the detoxification of alcohol- derived acetaldehyde (Probable). They are involved in the metabolism of corticosteroids, biogenic amines, neurotransmitters, and lipid peroxidation (Probable). Oxidizes medium and long chain aldehydes into non-toxic fatty acids (PubMed:1737758). Preferentially oxidizes aromatic aldehyde substrates (PubMed:1737758). Comprises about 50 percent of corneal epithelial soluble proteins (By similarity). May play a role in preventing corneal damage caused by ultraviolet light (By similarity). |
Cellular Location | Cytoplasm {ECO:0000250|UniProtKB:P47739}. |
Tissue Location | High levels in stomach, esophagus and lung; low level in the liver and kidney |
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Provided below are standard protocols that you may find useful for product applications.
Background
Reported variants represent identical protein: NP_001128639.1, NP_000682.3, NP_001128640.1
References
The oxidation status of ALDH3A1 in human saliva and its correlation with antioxidant capacity measured by ORAC method. Bogucka M, Giebu?towicz J, Zawada K, Wroczy?ski P, Wierzchowski J, Pietrzak M, Piekarczyk P, Romanowska K. Acta poloniae pharmaceutica 66 (5): 477-82. PMID: 19894643
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