c-Myb (aa557-569) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P10242 |
Other Accession | NP_001123645.1, NP_005366.2, NP_001123644.1, NP_001155128.1, NP_001155129.1, NP_001155130.1, NP_001155131.1, NP_001155132.1, 4602 |
Reactivity | Human |
Predicted | Mouse, Rat, Pig, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 72341 Da |
Gene ID | 4602 |
---|---|
Other Names | Transcriptional activator Myb, Proto-oncogene c-Myb, MYB |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | c-Myb (aa557-569) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MYB |
---|---|
Function | Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells. |
Cellular Location | Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:19646965} |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize all reported isofoms. (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1; NP_001155132.1).
References
c-Myb is required for pro-B cell differentiation. Fahl SP, Crittenden RB, Allman D, Bender TP. J Immunol. 2009 Nov 1;183(9):5582-92. PMID: 19843942
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