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c-Myb (aa557-569) Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - c-Myb (aa557-569) Antibody (internal region) AF3211a
    AF3211a (0.5 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P10242
Other Accession NP_001123645.1, NP_005366.2, NP_001123644.1, NP_001155128.1, NP_001155129.1, NP_001155130.1, NP_001155131.1, NP_001155132.1, 4602
Reactivity Human
Predicted Mouse, Rat, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 72341 Da
Additional Information
Gene ID 4602
Other Names Transcriptional activator Myb, Proto-oncogene c-Myb, MYB
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Precautionsc-Myb (aa557-569) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MYB
Function Transcriptional activator; DNA-binding protein that specifically recognize the sequence 5'-YAAC[GT]G-3'. Plays an important role in the control of proliferation and differentiation of hematopoietic progenitor cells.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00625, ECO:0000269|PubMed:19646965}
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognize all reported isofoms. (NP_001123645.1; NP_005366.2; NP_001123644.1; NP_001155128.1; NP_001155129.1; NP_001155130.1; NP_001155131.1; NP_001155132.1).

References

c-Myb is required for pro-B cell differentiation. Fahl SP, Crittenden RB, Allman D, Bender TP. J Immunol. 2009 Nov 1;183(9):5582-92. PMID: 19843942

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$ 341.00
Cat# AF3211a
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Availability: 7-10 days
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