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TOMM40 Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - TOMM40 Antibody (internal region) AF3090a
    AF3090a (2 µg/ml) staining of Human Frontal Cortex lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O96008
Other Accession NP_006105.1, 10452, 53333 (mouse), 308416 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 37893 Da
Additional Information
Gene ID 10452
Other Names Mitochondrial import receptor subunit TOM40 homolog, Protein Haymaker, Translocase of outer membrane 40 kDa subunit homolog, p38.5, TOMM40, C19orf1, PEREC1, TOM40
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTOMM40 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TOMM40
Synonyms C19orf1, PEREC1, TOM40
Function Channel-forming protein essential for import of protein precursors into mitochondria (PubMed:15644312, PubMed:31206022). Plays a role in the assembly of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) by forming a complex with BCAP31 and mediating the translocation of Complex I components from the cytosol to the mitochondria (PubMed:31206022).
Cellular Location Mitochondrion outer membrane; Multi-pass membrane protein. Note=Associates with the mitochondria- associated ER membrane via interaction with BCAP31
Research Areas
Citations (0)
citation

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Background

Reported variants represent identical protein: NP_001122389.1, NP_001122388.1, NP_006105.1.

References

Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers. Walker LC, Waddell N, Ten Haaf A, Grimmond S, Spurdle AB. Breast cancer research and treatment 2008 Nov 112 (2): 229-36. PMID: 18095154

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$ 341.00
Cat# AF3090a
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