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UBP1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q9NZI7 |
| Other Accession | NP_055332.3, NP_001121632.1, 7342, 22221 (mouse), 301038 (rat) |
| Predicted | Human, Mouse, Rat, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 60491 Da |
| Gene ID | 7342 |
|---|---|
| Other Names | Upstream-binding protein 1, Transcription factor LBP-1, UBP1, LBP1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | UBP1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | UBP1 |
|---|---|
| Synonyms | LBP1 |
| Function | Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA- box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. |
| Cellular Location | Nucleus. |
| Tissue Location | Expressed in adrenal tissue, JEG-3, NCI-H295A, Hep- G2 and HeLa cell lines. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Reported variants represent identical protein: NP_001121633.1, NP_055332.3.
References
LBP-1b, LBP-9, and LBP-32/MGR detected in syncytiotrophoblasts from first-trimester human placental tissue and their transcriptional regulation. Henderson YC, Frederick MJ, Wang MT, Hollier LM, Clayman GL, DNA and cell biology 2008 Feb 27 (2): 71-9. PMID: 18004979
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