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FGF8 Antibody (internal region)

Peptide-affinity purified goat antibody

     
  • WB - FGF8 Antibody (internal region) AF2909a
    AF2909a (2 µg/ml) staining of Jurkat lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P55075
Other Accession NP_149355.1, NP_006110.1, NP_149354.1, NP_149353.1, 2253
Reactivity Human
Predicted Mouse, Rat, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 26525 Da
Additional Information
Gene ID 2253
Other Names Fibroblast growth factor 8, FGF-8, Androgen-induced growth factor, AIGF, Heparin-binding growth factor 8, HBGF-8, FGF8, AIGF
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsFGF8 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FGF8
Synonyms AIGF
Function Plays an important role in the regulation of embryonic development, cell proliferation, cell differentiation and cell migration. Required for normal brain, eye, ear and limb development during embryogenesis. Required for normal development of the gonadotropin-releasing hormone (GnRH) neuronal system (PubMed:16384934, PubMed:16597617, PubMed:8663044). Plays a role in neurite outgrowth in hippocampal cells (PubMed:21576111).
Cellular Location Secreted.
Research Areas
Citations (0)
citation

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Background

This antibody is expected to recognize all reported isoforms (NP_149355.1; NP_006110.1; NP_149354.1; NP_149353.1)

References

FGFR2, FGF8, FGF10 and BMP7 as candidate genes for hypospadias. Beleza-Meireles A, Lundberg F, Lagerstedt K, Zhou X, Omrani D, Frisén L, Nordenskjöld A. Eur. J. Hum. Genet. 2007 Apr 15 (4): 405-10. PMID: 17264867

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$ 341.00
Cat# AF2909a
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