AGXT / AGT Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | P21549 |
Other Accession | NP_000021.1, 189 |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 43010 Da |
Gene ID | 189 |
---|---|
Other Names | Serine--pyruvate aminotransferase, SPT, 2.6.1.51, Alanine--glyoxylate aminotransferase, AGT, 2.6.1.44, AGXT, AGT1, SPAT |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | AGXT / AGT Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | AGXT (HGNC:341) |
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Synonyms | AGT1, SPAT |
Function | Peroxisomal aminotransferase that catalyzes the transamination of glyoxylate to glycine and contributes to the glyoxylate detoxification (PubMed:10960483, PubMed:12777626, PubMed:23229545, PubMed:24055001, PubMed:26149463). Also catalyzes the transamination between L-serine and pyruvate and contributes to gluconeogenesis from the L-serine metabolism (PubMed:10347152). |
Cellular Location | Peroxisome |
Tissue Location | Liver. |
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Provided below are standard protocols that you may find useful for product applications.
References
Molecular etiology of primary hyperoxaluria type 1: new directions for treatment. Danpure CJ. Am J Nephrol. 2005 May-Jun;25(3):303-10. PMID: 15961951
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