LAMA3 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q16787 |
Other Accession | NP_937762.1, 3909 |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 366619 Da |
Gene ID | 3909 |
---|---|
Other Names | Laminin subunit alpha-3, Epiligrin 170 kDa subunit, E170, Epiligrin subunit alpha, Kalinin subunit alpha, Laminin-5 subunit alpha, Laminin-6 subunit alpha, Laminin-7 subunit alpha, Nicein subunit alpha, LAMA3, LAMNA |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | LAMA3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LAMA3 |
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Synonyms | LAMNA |
Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. |
Cellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component |
Tissue Location | Skin; respiratory, urinary, and digestive epithelia and in other specialized tissues with prominent secretory or protective functions. Epithelial basement membrane, and epithelial cell tongue that migrates into a wound bed. A differential and focal expression of the subunit alpha-3 is observed in the CNS |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognise isoform 1 (NP_937762.1) only.
References
CREB-binding protein regulates apoptosis and growth of HMECs grown in reconstituted ECM via laminin-5. Dietze EC, Bowie ML, Mrozek K, Caldwell LE, Neal C, Marjoram RJ, Troch MM, Bean GR, Yokoyama KK, Ibarra CA, Seewaldt VL. J Cell Sci. 2005 Nov 1;118(Pt 21):5005-22. Epub 2005 Oct 11. PMID: 16219677
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