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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > NOTCH3 Antibody (C-Term)
NOTCH3 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| IHC, E |
|---|---|
| Primary Accession | Q9UM47 |
| Other Accession | NP_000426.2, 4854 |
| Predicted | Human, Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 243631 Da |
| Gene ID | 4854 |
|---|---|
| Other Names | Neurogenic locus notch homolog protein 3, Notch 3, Notch 3 extracellular truncation, Notch 3 intracellular domain, NOTCH3 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | NOTCH3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | NOTCH3 |
|---|---|
| Function | Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination (PubMed:15350543). Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs (By similarity). |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Ubiquitously expressed in fetal and adult tissues. |
Research Areas
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$ 464.00
Cat# AF2474a
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