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Histamine Receptor H1 (C Term) Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS: 1
- PROTOCOLS
- BACKGROUND
Application 
| IHC, IF, FC, Pep-ELISA |
|---|---|
| Primary Accession | P35367 |
| Other Accession | NP_000852.1, NP_001091681.1, NP_001091682.1, NP_001091683.1, 3269, 15465 (mouse), 24448 (rat) |
| Reactivity | Human |
| Predicted | Mouse, Rat, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 55784 Da |
| Gene ID | 3269 |
|---|---|
| Other Names | Histamine H1 receptor, H1R, HH1R, HRH1 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Histamine Receptor H1 (C Term) Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HRH1 (HGNC:5182) |
|---|---|
| Function | G-protein-coupled receptor for histamine, a biogenic amine that functions as an immune modulator and a neurotransmitter (PubMed:33828102, PubMed:8280179). Through the H1 receptor, histamine mediates the contraction of smooth muscles and increases capillary permeability due to contraction of terminal venules. Also mediates neurotransmission in the central nervous system and thereby regulates circadian rhythms, emotional and locomotor activities as well as cognitive functions (By similarity). |
| Cellular Location | Cell membrane; Multi-pass membrane protein |
Provided below are standard protocols that you may find useful for product applications.
Background
Variants (NP_000852.1; NP_001091681.1; NP_001091682.1; NP_001091683.1) encode the same protein.
References
Beta(2)-adrenergic receptor-mediated histamine H(1) receptor down-regulation: another possible advantage of beta(2) agonists in asthmatic therapy. Kawakami N, Miyoshi K, Horio S, Fukui H. J Pharmacol Sci. 2004 Apr;94(4):449-58. PMID: 15107586
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