CFC1 / Cripto-1 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC, E |
---|---|
Primary Accession | P0CG37 |
Other Accession | NP_115934.1, 55997 |
Reactivity | Mouse |
Predicted | Human, Rat |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 24612 Da |
Gene ID | 55997 |
---|---|
Other Names | Cryptic protein, Cryptic family protein 1, CFC1 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | CFC1 / Cripto-1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CFC1 |
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Function | NODAL coreceptor involved in the correct establishment of the left-right axis. May play a role in mesoderm and/or neural patterning during gastrulation. |
Cellular Location | Cell membrane; Lipid-anchor, GPI-anchor. Secreted. Note=Does not exhibit a typical GPI- signal sequence. The C-ter hydrophilic extension of the GPI-signal sequence reduces the efficiency of processing and could lead to the production of an secreted unprocessed form. This extension is found only in primates |
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Provided below are standard protocols that you may find useful for product applications.
References
Role of human cripto-1 in tumor angiogenesis. Bianco C, Strizzi L, Ebert A, Chang C, Rehman A, Normanno N, Guedez L, Salloum R, Ginsburg E, Sun Y, Khan N, Hirota M, Wallace-Jones B, Wechselberger C, Vonderhaar BK, Tosato G, Stetler-Stevenson WG, Sanicola M, Salomon DS. J Natl Cancer Inst. 2005 Jan 19;97(2):132-41. PMID: 15657343
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