Integrin beta 5 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | P18084 |
Other Accession | NP_002204.2, 3693, 16419 (mouse) |
Reactivity | Human, Mouse |
Predicted | Rat, Pig, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 88054 Da |
Gene ID | 3693 |
---|---|
Other Names | Integrin beta-5, ITGB5 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Integrin beta 5 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | ITGB5 |
---|---|
Function | Integrin alpha-V/beta-5 (ITGAV:ITGB5) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligand. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
References
Phagocytosis of rod outer segments by retinal pigment epithelial cells requires alpha(v)beta5 integrin for binding but not for internalization. Finnemann SC, Bonilha VL, Marmorstein AD, Rodriguez-Boulan E. Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12932-7. PMID: 9371778
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