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EndoNEDD4 / NEDL2 Antibody (N-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | Q9P2P5 |
| Other Accession | NP_065811.1, 57520, 227106 (mouse) |
| Predicted | Human, Mouse, Rat |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 175769 Da |
| Gene ID | 57520 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase HECW2, 6.3.2.-, HECT, C2 and WW domain-containing protein 2, NEDD4-like E3 ubiquitin-protein ligase 2, HECW2, KIAA1301, NEDL2 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | EndoNEDD4 / NEDL2 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | HECW2 |
|---|---|
| Synonyms | KIAA1301, NEDL2 |
| Function | E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73 (PubMed:12890487). Involved in the regulation of mitotic metaphase/anaphase transition (PubMed:24163370). |
| Cellular Location | Cytoplasm. Cytoplasm, cytoskeleton, spindle |
| Tissue Location | Predominantly expressed in adult brain, lung and heart. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro. Nagase T, Kikuno R, Ishikawa KI, Hirosawa M, Ohara O. DNA Res. 2000 Feb 28;7(1):65-73. PMID: 10718198
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