Goat Anti-PALS2 / VAM1 / MPP6 Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q9NZW5 |
Other Accession | NP_057531, 51678, 56524 (mouse) |
Reactivity | Human |
Predicted | Mouse, Rat, Pig, Dog |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 61117 Da |
Gene ID | 51678 |
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Other Names | MAGUK p55 subfamily member 6, Veli-associated MAGUK 1, VAM-1, MPP6, VAM1 |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-PALS2 / VAM1 / MPP6 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PALS2 (HGNC:18167) |
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Synonyms | MPP6, VAM1 |
Cellular Location | Membrane; Peripheral membrane protein |
Tissue Location | Abundant in testis, brain, and kidney with lower levels detectable in other tissues |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the peripheral membrane-associated guanylate kinase (MAGUK) family function in tumor suppression and receptor clustering by forming multiprotein complexes containing distinct sets of transmembrane, cytoskeletal, and cytoplasmic signaling proteins. All MAGUKs contain a PDZ-SH3-GUK core and are divided into 4 subfamilies, DLG-like (see DLG1; MIM 601014), ZO1-like (see TJP1; MIM 601009), p55-like (see MPP1; MIM 305360), and LIN2-like (see CASK; MIM 300172), based on their size and the presence of additional domains. MPP6 is a member of the p55-like MAGUK subfamily (Tseng et al., 2001 [PubMed 11311936]).
References
Prospective 7 year follow up imaging study comparing radiography, ultrasonography, and magnetic resonance imaging in rheumatoid arthritis finger joints. Scheel AK, et al. Ann Rheum Dis, 2006 May. PMID 16192290.
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Rush J, et al. Nat Biotechnol, 2005 Jan. PMID 15592455.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
A protein interaction framework for human mRNA degradation. Lehner B, et al. Genome Res, 2004 Jul. PMID 15231747.
Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. Leonoudakis D, et al. J Biol Chem, 2004 May 21. PMID 15024025.
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