Goat Anti-LDHC (aa 217 - 231) Antibody
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, E |
---|---|
Primary Accession | P07864 |
Other Accession | NP_059144, 3948, 16833 (mouse) |
Reactivity | Mouse |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 100ug/200ul |
Isotype | IgG |
Calculated MW | 36311 Da |
Gene ID | 3948 |
---|---|
Other Names | L-lactate dehydrogenase C chain, LDH-C, 1.1.1.27, Cancer/testis antigen 32, CT32, LDH testis subunit, LDH-X, LDHC, LDH3, LDHX |
Format | 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | Goat Anti-LDHC (aa 217 - 231) Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | LDHC |
---|---|
Synonyms | LDH3, LDHX |
Function | Possible role in sperm motility. |
Cellular Location | Cytoplasm. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Lactate dehydrogenase C catalyzes the conversion of L-lactate and NAD to pyruvate and NADH in the final step of anaerobic glycolysis. LDHC is testis-specific and belongs to the lactate dehydrogenase family. Two transcript variants have been detected which differ in the 5' untranslated region.
References
Homo sapiens lactate dehydrogenase c (Ldhc) gene expression in cancer cells is regulated by transcription factor Sp1, CREB, and CpG island methylation. Tang H, et al. J Androl, 2009 Mar-Apr. PMID 18930904.
Construction of sperm-specific lactate dehydrogenase DNA vaccine and experimental study of its immunocontraceptive effect on mice. Chen Y, et al. Sci China C Life Sci, 2008 Apr. PMID 18368308.
Elevated level of serum LDH2 and LDH3 in sputum three positive TB patients of Sahariya tribe: a preliminary study. Sharma PR, et al. Clin Biochem, 2007 Dec. PMID 17935709.
Increased serum lactate dehydrogenase isoenzymes in Ph-negative chronic myeloproliferative diseases: a metabolic adaptation? Mazzotta S, et al. Hematology, 2006 Aug. PMID 17178662.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
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