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Goat Anti-Latexin Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-Latexin Antibody AF1617a
    AF1617a (0.1 µg/ml) staining of Rat Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IHC, IF, E
Primary Accession Q9BS40
Other Accession NP_064554, 56925, 17035 (mouse), 59073 (rat)
Reactivity Human, Mouse, Rat
Predicted Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 25750 Da
Additional Information
Gene ID 56925
Other Names Latexin, Endogenous carboxypeptidase inhibitor, ECI, Protein MUM, Tissue carboxypeptidase inhibitor, TCI, LXN
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-Latexin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LXN
Function Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation.
Cellular Location Cytoplasm.
Tissue Location Highly expressed in heart, prostate, ovary, kidney, pancreas, and colon, moderate or low in other tissues including brain
Research Areas
Citations (0)
citation

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Background

This gene encodes the only known protein inhibitor of zinc-dependent metallocarboxypeptidases.

References

Large-scale mapping of human protein-protein interactions by mass spectrometry. Ewing RM, et al. Mol Syst Biol, 2007. PMID 17353931.
Structure of human carboxypeptidase A4 with its endogenous protein inhibitor, latexin. Pallar脷s I, et al. Proc Natl Acad Sci U S A, 2005 Mar 15. PMID 15738388.
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932.
Cloning, tissue expression pattern and genomic organization of latexin, a human homologue of rat carboxypeptidase A inhibitor. Liu Q, et al. Mol Biol Rep, 2000. PMID 11455960.

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$ 341.00
Cat# AF1617a
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