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Goat Anti-FOXG1 / BF2 Antibody

Peptide-affinity purified goat antibody

     
  • WB - Goat Anti-FOXG1 / BF2 Antibody AF1430a
    AF1430a (0.3 µg/ml) staining of Human Brain lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IF, ICC, E
Primary Accession P55316
Other Accession NP_005240, 2290, 15228 (mouse), 24370 (rat)
Reactivity Human, Mouse
Predicted Rat, Dog
Host Goat
Clonality Polyclonal
Concentration 100ug/200ul
Isotype IgG
Calculated MW 52352 Da
Additional Information
Gene ID 2290
Other Names Forkhead box protein G1, Brain factor 1, BF-1, BF1, Brain factor 2, BF-2, BF2, hBF-2, Forkhead box protein G1A, Forkhead box protein G1B, Forkhead box protein G1C, Forkhead-related protein FKHL1, HFK1, Forkhead-related protein FKHL2, HFK2, Forkhead-related protein FKHL3, HFK3, FOXG1
Format 0.5 mg IgG/ml in Tris saline (20mM Tris pH7.3, 150mM NaCl), 0.02% sodium azide, with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGoat Anti-FOXG1 / BF2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name FOXG1
Function Transcription repression factor which plays an important role in the establishment of the regional subdivision of the developing brain and in the development of the telencephalon.
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00089, ECO:0000269|PubMed:21280142}
Tissue Location Expression is restricted to the neurons of the developing telencephalon.
Research Areas
Citations (0)
citation

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Background

This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in the development of the brain and telencephalon.

References

Epilepsy in Rett syndrome: Clinical and genetic features. Pintaudi M, et al. Epilepsy Behav, 2010 Aug 20. PMID 20728410.
Revisiting the phenotype associated with FOXG1 mutations: two novel cases of congenital Rett variant. Bahi-Buisson N, et al. Neurogenetics, 2010 May. PMID 19806373.
Novel FOXG1 mutations associated with the congenital variant of Rett syndrome. Mencarelli MA, et al. J Med Genet, 2010 Jan. PMID 19578037.
Phenotypic variability in Rett syndrome associated with FOXG1 mutations in females. Philippe C, et al. J Med Genet, 2010 Jan. PMID 19564653.
FOXG1 is responsible for the congenital variant of Rett syndrome. Ariani F, et al. Am J Hum Genet, 2008 Jul. PMID 18571142.

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$ 341.00
Cat# AF1430a
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