BG8,Lewisy
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P |
---|---|
Primary Accession | P21217 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 233L1D5 |
Calculated MW | 42117 Da |
Gene ID | 2525 |
---|---|
Gene Name | FUT3 |
Other Names | 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT3, 2.4.1.65, 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase, 2.4.1.152, Alpha-3-fucosyltransferase FUT3, 2.4.1.-, Blood group Lewis alpha-4-fucosyltransferase, Lewis FT, Fucosyltransferase 3, Fucosyltransferase III, FucT-III, FUT3 (HGNC:4014), FT3B, LE |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C |
Precautions | BG8,Lewisy Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FUT3 (HGNC:4014) |
---|---|
Synonyms | FT3B, LE |
Function | May catalyze alpha-1,3 and alpha-1,4 glycosidic linkages involved in the expression of Vim-2, Lewis A, Lewis B, sialyl Lewis X and Lewis X/SSEA-1 antigens. May be involved in blood group Lewis determination; Lewis-positive (Le(+)) individuals have an active enzyme while Lewis-negative (Le(-)) individuals have an inactive enzyme. Also acts on the corresponding 1,4-galactosyl derivative, forming 1,3-L-fucosyl links. |
Cellular Location | Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi |
Tissue Location | Highly expressed in stomach, colon, small intestine, lung and kidney and to a lesser extent in salivary gland, bladder, uterus and liver |

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