Anti-Thrombomodulin
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P07204 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 746E8A9 |
Calculated MW | 60329 Da |
Gene ID | 7056 |
---|---|
Gene Name | THBD |
Other Names | Thrombomodulin, TM, Fetomodulin, CD141, THBD, THRM |
Dilution | IHC-P~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C |
Precautions | Thrombomodulin Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | THBD |
---|---|
Synonyms | THRM |
Function | Thrombomodulin is a specific endothelial cell receptor that forms a 1:1 stoichiometric complex with thrombin. This complex is responsible for the conversion of protein C to the activated protein C (protein Ca). Once evolved, protein Ca scissions the activated cofactors of the coagulation mechanism, factor Va and factor VIIIa, and thereby reduces the amount of thrombin generated. |
Cellular Location | Membrane; Single-pass type I membrane protein |
Tissue Location | Endothelial cells are unique in synthesizing thrombomodulin |
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