p16
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P42771 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 598A6G3 |
Calculated MW | 16533 Da |
Gene ID | 1029 |
---|---|
Gene Name | CDKN2A (HGNC:1787) |
Other Names | Cyclin-dependent kinase inhibitor 2A {ECO:0000312|HGNC:HGNC:1787}, Cyclin-dependent kinase 4 inhibitor A, CDK4I, Multiple tumor suppressor 1, MTS-1, p16-INK4a, p16-INK4, p16INK4A, CDKN2A (HGNC:1787), CDKN2, MTS1 |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | This product is stored at 2-8 ℃, please use it within the expiration date. |
Precautions | p16 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDKN2A (HGNC:1787) |
---|---|
Synonyms | CDKN2, MTS1 |
Function | Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein. |
Cellular Location | Cytoplasm. Nucleus |
Tissue Location | Widely expressed but not detected in brain or skeletal muscle. Isoform 3 is pancreas-specific |
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