SOX-10
Rabbit Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P56693 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone Names | 908G6C7 |
Calculated MW | 49911 Da |
Gene ID | 6663 |
---|---|
Gene Name | SOX10 |
Other Names | Transcription factor SOX-10, SOX10 |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | This product is stored at 2-8 ℃, please use it within the expiration date. |
Precautions | SOX-10 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SOX10 |
---|---|
Function | Transcription factor that plays a central role in developing and mature glia. Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination. Once induced, MYRF cooperates with SOX10 to implement the myelination program. Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). |
Cellular Location | Cytoplasm. Nucleus. Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q04888}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q04888}; Cytoplasmic side {ECO:0000250|UniProtKB:Q04888} |
Tissue Location | Expressed in fetal brain and in adult brain, heart, small intestine and colon |
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