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TFE3
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| IHC-P |
|---|---|
| Primary Accession | P19532 |
| Reactivity | Human |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone Names | 676G3H2 |
| Calculated MW | 61521 Da |
| Gene ID | 7030 |
|---|---|
| Gene Name | TFE3 |
| Other Names | Transcription factor E3, Class E basic helix-loop-helix protein 33, bHLHe33, TFE3 {ECO:0000303|PubMed:9393982, ECO:0000312|HGNC:HGNC:11752} |
| Dilution | IHC-P~~Ready-to-use |
| Storage | This product is stored at 2-8 ℃, please use it within the expiration date. |
| Precautions | TFE3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TFE3 {ECO:0000303|PubMed:9393982, ECO:0000312|HGNC:HGNC:11752} |
|---|---|
| Synonyms | BHLHE33 |
| Function | Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T- cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. |
| Cellular Location | Nucleus. |
| Tissue Location | Ubiquitous in fetal and adult tissues. |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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If you have any additional inquiries please email technical services at tech@abcepta.com.
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Cat# AD80203-010
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