p57
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P49918 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 524F9C6 |
Calculated MW | 32177 Da |
Gene ID | 1028 |
---|---|
Gene Name | CDKN1C |
Other Names | Cyclin-dependent kinase inhibitor 1C, Cyclin-dependent kinase inhibitor p57, p57Kip2, CDKN1C, KIP2 |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | This product is stored at 2-8 ℃, please use it within the expiration date. |
Precautions | p57 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | CDKN1C |
---|---|
Synonyms | KIP2 |
Function | Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non- proliferative state throughout life. |
Cellular Location | Nucleus. |
Tissue Location | Expressed in the heart, brain, lung, skeletal muscle, kidney, pancreas and testis. Expressed in the eye. High levels are seen in the placenta while low levels are seen in the liver. |
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