CK14
Mouse Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P |
---|---|
Primary Accession | P02533 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Clone Names | 129F6G3 |
Calculated MW | 51561 Da |
Gene ID | 3861 |
---|---|
Gene Name | KRT14 |
Other Names | Keratin, type I cytoskeletal 14, Cytokeratin-14, CK-14, Keratin-14, K14, KRT14 |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C |
Precautions | CK14 Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KRT14 |
---|---|
Function | The nonhelical tail domain is involved in promoting KRT5-KRT14 filaments to self-organize into large bundles and enhances the mechanical properties involved in resilience of keratin intermediate filaments in vitro. |
Cellular Location | Cytoplasm. Nucleus. Note=Expressed in both as a filamentous pattern |
Tissue Location | Detected in the basal layer, lowered within the more apically located layers specifically in the stratum spinosum, stratum granulosum but is not detected in stratum corneum. Strongly expressed in the outer root sheath of anagen follicles but not in the germinative matrix, inner root sheath or hair. Found in keratinocytes surrounding the club hair during telogen. |

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