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SOX-2

Rabbit Monoclonal antibody(Mab)

     
  • IHC-P - SOX-2 AD80115-010
    Lung squamous cell carcinoma
    detail
  • IHC - SOX-2 AD80115-010
    Immunohistochemical analysis of paraffin-embedded human lung squamous carcinoma tissue using AD80277 performed on the Abcarta® FAIP-30 Fully automated IHC platform.Tissue was fixed with formaldehyde at room temperature, antigen retrieval was by heat mediation with a EDTA buffer (pH9. 0). Samples were incubated with primary antibody(Ready-to-use) for 15 min at room temperature. AmpSeeTM Detection Systems(Abcepta:AR005) was used as the secondary antibody.
    detail
  • SPECIFICATION
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Product info
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
IHC-P
Primary Accession P48431
Reactivity Human
Host Rabbit
Clonality Monoclonal
Clone Names 526B2H4
Calculated MW 34310 Da
Additional info
Gene ID 6657
Gene Name SOX2
Other Names Transcription factor SOX-2, SOX2
Dilution IHC-P~~Ready-to-use
IHC~~Ready-to-use
Storage This product is stored at 2-8 ℃, please use it within the expiration date.
Precautions SOX-2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SOX2
Function Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
Cellular Location Nucleus.
Research Areas
Citations (0)
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$ 106.00
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$ 291.00
Cat# AD80115-010
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