PSAP
Rabbit Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| IHC-P |
---|---|
Primary Accession | P07602 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone Names | 216B5D8 |
Calculated MW | 58113 Da |
Gene ID | 5660 |
---|---|
Gene Name | PSAP |
Other Names | Prosaposin, Proactivator polypeptide, Saposin-A, Protein A, Saposin-B-Val, Saposin-B, Cerebroside sulfate activator, CSAct, Dispersin, Sphingolipid activator protein 1, SAP-1, Sulfatide/GM1 activator, Saposin-C, A1 activator, Co-beta-glucosidase, Glucosylceramidase activator, Sphingolipid activator protein 2, SAP-2, Saposin-D, Component C, Protein C, PSAP, GLBA, SAP1 |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | Maintain refrigerated at 2-8°C |
Precautions | PSAP Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PSAP |
---|---|
Synonyms | GLBA, SAP1 |
Function | Saposin-A and saposin-C stimulate the hydrolysis of glucosylceramide by beta-glucosylceramidase (EC 3.2.1.45) and galactosylceramide by beta-galactosylceramidase (EC 3.2.1.46). Saposin-C apparently acts by combining with the enzyme and acidic lipid to form an activated complex, rather than by solubilizing the substrate. Saposin-D is a specific sphingomyelin phosphodiesterase activator (EC 3.1.4.12). Saposins are specific low-molecular mass non-enzymic proteins, they participate in the lysosomal degradation of sphingolipids, which takes place by the sequential action of specific hydrolases. |
Cellular Location | Lysosome |

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