TOP2A
Rabbit Monoclonal antibody(Mab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| IHC-P |
---|---|
Primary Accession | P11388 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Clone Names | 221B4D2 |
Calculated MW | 174385 Da |
Gene ID | 7153 |
---|---|
Gene Name | TOP2A |
Other Names | DNA topoisomerase 2-alpha, 5.6.2.2 {ECO:0000255|PROSITE-ProRule:PRU00995, ECO:0000269|PubMed:19222228, ECO:0000269|PubMed:19697956}, DNA topoisomerase II, alpha isozyme, TOP2A, TOP2 |
Dilution | IHC-P~~Ready-to-use IHC~~Ready-to-use |
Storage | This product is stored at 2-8 ℃, please use it within the expiration date. |
Precautions | TOP2A Antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | TOP2A |
---|---|
Synonyms | TOP2 |
Function | Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity). |
Cellular Location | Cytoplasm. Nucleus, nucleoplasm. Note=Generally located in the nucleoplasm |
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