Anti-human Flotillin antibody
Purified Rabbit Polyclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, FC, E |
---|---|
Primary Accession | O75955 |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Isotype | Rabbit IgG |
Calculated MW | 47355 Da |
Gene ID | 10211 |
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Other Names | Flotillin-1, FLOT1 |
Target/Specificity | Flotilin (unconjugated) |
Formulation | 0.2 mg/ml in phosphate buffered saline (PBS) with sodium azide (15 mM), Approx. pH 7.4. |
Handling | The antibody solution should be gently mixed before use |
Background Descriptions | |
Precautions | Anti-human Flotillin antibody is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | FLOT1 |
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Function | May act as a scaffolding protein within caveolar membranes, functionally participating in formation of caveolae or caveolae-like vesicles. |
Cellular Location | Cell membrane; Peripheral membrane protein. Endosome Membrane, caveola {ECO:0000250|UniProtKB:O08917}; Peripheral membrane protein {ECO:0000250|UniProtKB:O08917}. Melanosome. Membrane raft. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065) Membrane-associated protein of caveola (By similarity) {ECO:0000250|UniProtKB:O08917, ECO:0000269|PubMed:17081065} |

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Provided below are standard protocols that you may find useful for product applications.
Background
Flotillin belongs to the band 7.2/stomatin protein family and appears to be strongly expressed in muscle cells and fibroblasts. Flotillin expression is also correlated with Alzheimer development. Flotillin is highly expressed on exosomes and appears to be involved in exosome release. It is considered a common marker for exosomes analyses.

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