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> home > Products > Primary Antibodies > Antibody Collections > Ovary positive > Anti-HN1 Rabbit Monoclonal Antibody
Anti-HN1 Rabbit Monoclonal Antibody
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Application 
| WB, FC |
|---|---|
| Primary Accession | Q9UK76 |
| Host | Rabbit |
| Isotype | Rabbit IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-HN1 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 51155 |
|---|---|
| Other Names | Jupiter microtubule associated homolog 1 {ECO:0000312|HGNC:HGNC:14569}, Androgen-regulated protein 2, Hematological and neurological expressed 1 protein, Jupiter microtubule associated homolog 1, N-terminally processed, JPT1 (HGNC:14569) |
| Calculated MW | 16015 Da |
| Application Details | WB 1:500-1:2000 ICC/IF 1:50-1:200 FC 1:50 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 31J27 |
| Immunogen | A synthesized peptide derived from human HN1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | JPT1 (HGNC:14569) |
|---|---|
| Function | Modulates negatively AKT-mediated GSK3B signaling (PubMed:21323578, PubMed:22155408). Induces CTNNB1 'Ser-33' phosphorylation and degradation through the suppression of the inhibitory 'Ser-9' phosphorylation of GSK3B, which represses the function of the APC:CTNNB1:GSK3B complex and the interaction with CDH1/E-cadherin in adherent junctions (PubMed:25169422). Plays a role in the regulation of cell cycle and cell adhesion (PubMed:25169422, PubMed:25450365). Has an inhibitory role on AR-signaling pathway through the induction of receptor proteasomal degradation (PubMed:22155408). |
| Cellular Location | Nucleus. Cytoplasm |
| Tissue Location | Expressed in testis, skeletal muscle, thymus, prostate, colon, peripheral blood cells, brain and placenta |
Research Areas
Citations (0)
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO16656
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