Anti-Gamma glutamyl hydrolase Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB |
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Primary Accession | Q92820 |
Host | Rabbit |
Isotype | Rabbit IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Gamma glutamyl hydrolase Rabbit Monoclonal Antibody . Tested in WB applications. This antibody reacts with Human. |
Gene ID | 8836 |
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Other Names | Gamma-glutamyl hydrolase, 3.4.19.9, Conjugase, GH, Gamma-Glu-X carboxypeptidase, GGH (HGNC:4248) |
Calculated MW | 35964 Da |
Application Details | WB 1:500-1:2000 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 31G17 |
Immunogen | A synthesized peptide derived from human Gamma glutamyl hydrolase |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | GGH (HGNC:4248) |
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Function | Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha-glutamate (folic acid) and free glutamate (PubMed:11005824, PubMed:8816764). May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates. |
Cellular Location | Secreted, extracellular space. Lysosome. Melanosome. Note=While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted Identified by mass spectrometry in melanosome fractions from stage I to stage IV. |
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