Anti-NSDHL Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IP |
---|---|
Primary Accession | Q15738 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-NSDHL Rabbit Monoclonal Antibody . Tested in WB, IP applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 50814 |
---|---|
Other Names | Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating, 1.1.1.170, Protein H105e3, NSDHL, H105E3 |
Calculated MW | 38 kDa |
Application Details | WB 1:500-1:2000 IP 1:50 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 30N66 |
Immunogen | A synthesized peptide derived from human NSDHL |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | NSDHL |
---|---|
Synonyms | H105E3 |
Function | Catalyzes the NAD(P)(+)-dependent oxidative decarboxylation of the C4 methyl groups of 4-alpha-carboxysterols in post-squalene cholesterol biosynthesis (By similarity). Also plays a role in the regulation of the endocytic trafficking of EGFR (By similarity). |
Cellular Location | Endoplasmic reticulum membrane; Single-pass membrane protein. Lipid droplet {ECO:0000250|UniProtKB:Q9R1J0} Note=Trafficking through the Golgi is necessary for ER membrane localization. {ECO:0000250|UniProtKB:Q9R1J0} |
Tissue Location | Brain, heart, liver, lung, kidney, skin and placenta |
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