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> home > Products > Primary Antibodies > Antibody Collections > Thyroid gland negative > Anti-NCS1 Rabbit Monoclonal Antibody
Anti-NCS1 Rabbit Monoclonal Antibody
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Application 
| WB, IHC, FC |
|---|---|
| Primary Accession | P62166 |
| Host | Rabbit |
| Isotype | IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-NCS1 Rabbit Monoclonal Antibody . Tested in WB, IHC, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 23413 |
|---|---|
| Other Names | Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, NCS1, FLUP, FREQ |
| Calculated MW | 22 kDa |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 FC 1:50 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 26N80 |
| Immunogen | A synthesized peptide derived from human NCS1 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | NCS1 |
|---|---|
| Synonyms | FLUP, FREQ |
| Function | Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage- gated calcium channel (By similarity). |
| Cellular Location | Golgi apparatus. Postsynaptic density. Cytoplasm, perinuclear region. Cytoplasm {ECO:0000250|UniProtKB:P62168}. Cell membrane; Peripheral membrane protein. Membrane {ECO:0000250|UniProtKB:P62168}; Lipid-anchor Note=Associated with Golgi stacks. Post-synaptic densities of dendrites, and in the pre-synaptic nerve terminal at neuromuscular junctions. {ECO:0000305, ECO:0000305|PubMed:17555535} |
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Application Protocols
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$ 370.00
Cat# ABO16101
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