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Anti-MDH1 Rabbit Monoclonal Antibody

     
  •  - Anti-MDH1 Rabbit Monoclonal Antibody ABO15748
    Western blot analysis of MDH1 expression in HeLa cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IF, ICC, IP, FC
Primary Accession P40925
Host Rabbit
Isotype IgG
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Format Liquid
Description Anti-MDH1 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Additional Information
Gene ID 4190
Other Names Malate dehydrogenase, cytoplasmic, 1.1.1.37, Aromatic alpha-keto acid reductase, KAR, 1.1.1.96, Cytosolic malate dehydrogenase, MDH1 {ECO:0000303|PubMed:34012073, ECO:0000312|HGNC:HGNC:6970}
Calculated MW 36 kDa
Application Details WB 1:1000-1:5000
ICC/IF 1:50-1:200
IP 1:50
FC 1:30
Contents Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clone Names Clone: 23M24
Immunogen A synthesized peptide derived from human MDH1
Purification Affinity-chromatography
Storage Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Information
Name MDH1 {ECO:0000303|PubMed:34012073, ECO:0000312|HGNC:HGNC:6970}
Function Catalyzes the reduction of aromatic alpha-keto acids in the presence of NADH (PubMed:2449162, PubMed:3052244). Plays essential roles in the malate-aspartate shuttle and the tricarboxylic acid cycle, important in mitochondrial NADH supply for oxidative phosphorylation (PubMed:31538237). Catalyzes the reduction of 2-oxoglutarate to 2- hydroxyglutarate, leading to elevated reactive oxygen species (ROS) (PubMed:34012073).
Cellular Location Cytoplasm, cytosol.
Research Areas
Citations (0)
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$ 370.00
Cat# ABO15748
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