Anti-TXNRD2 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC |
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Primary Accession | Q9NNW7 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-TXNRD2 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 10587 |
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Other Names | Thioredoxin reductase 2, mitochondrial, 1.8.1.9, Selenoprotein Z, SelZ, TR-beta, Thioredoxin reductase TR3, TXNRD2 (HGNC:18155), KIAA1652, TRXR2 |
Calculated MW | 56 kDa |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 23T23 |
Immunogen | A synthesized peptide derived from human TXNRD2 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | TXNRD2 (HGNC:18155) |
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Synonyms | KIAA1652, TRXR2 |
Function | Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis (PubMed:24601690). Maintains thioredoxin in a reduced state. May play a role in redox- regulated cell signaling. |
Cellular Location | Mitochondrion. |
Tissue Location | Highly expressed in the prostate, ovary, liver, testis, uterus, colon and small intestine. Intermediate levels in brain, skeletal muscle, heart and spleen. Low levels in placenta, pancreas, thymus and peripheral blood leukocytes. According to PubMed:10608886, high levels in kidney, whereas according to PubMed:9923614, levels are low. High expression is observed in the adrenal cortex (PubMed:24601690). |
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