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> home > Products > Primary Antibodies > Signal Transduction > Anti-ENTPD5 Rabbit Monoclonal Antibody
Anti-ENTPD5 Rabbit Monoclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | O75356 |
| Host | Rabbit |
| Isotype | IgG |
| Reactivity | Rat, Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-ENTPD5 Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human, Mouse, Rat. |
| Gene ID | 957 |
|---|---|
| Other Names | Nucleoside diphosphate phosphatase ENTPD5, 3.6.1.6, CD39 antigen-like 4, ER-UDPase, Ectonucleoside triphosphate diphosphohydrolase 5 {ECO:0000312|HGNC:HGNC:3367}, NTPDase 5, Guanosine-diphosphatase ENTPD5, GDPase ENTPD5, Inosine diphosphate phosphatase ENTPD5, Nucleoside diphosphatase, Uridine-diphosphatase ENTPD5, UDPase ENTPD5, ENTPD5 (HGNC:3367) |
| Calculated MW | 47 kDa |
| Application Details | WB 1:500-1:2000 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 21E75 |
| Immunogen | A synthesized peptide derived from human ENTPD5 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | ENTPD5 (HGNC:3367) |
|---|---|
| Function | Hydrolyzes nucleoside diphosphates with a preference for GDP, IDP and UDP compared to ADP and CDP (PubMed:10400613, PubMed:15698960). In the lumen of the endoplasmic reticulum, hydrolyzes UDP that acts as an end-product feedback inhibitor of the UDP-Glc:glycoprotein glucosyltransferases. UMP can be transported back by an UDP-sugar antiporter to the cytosol where it is consumed to regenerate UDP- glucose. Therefore, it positively regulates protein reglucosylation by clearing UDP from the ER lumen and by promoting the regeneration of UDP-glucose. Protein reglucosylation is essential to proper glycoprotein folding and quality control in the ER (By similarity). |
| Cellular Location | Endoplasmic reticulum {ECO:0000250|UniProtKB:Q9WUZ9}. Secreted |
| Tissue Location | Expressed in adult liver, kidney, prostate, testis and colon. Much weaker expression in other tissues |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO15599
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