Anti-ATAD2 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IF, ICC, FC |
---|---|
Primary Accession | Q6PL18 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Human |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-ATAD2 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, Flow Cytometry applications. This antibody reacts with Human. |
Gene ID | 29028 |
---|---|
Other Names | ATPase family AAA domain-containing protein 2, 3.6.1.-, AAA nuclear coregulator cancer-associated protein, ANCCA, ATAD2 |
Calculated MW | 180 kDa |
Application Details | WB 1:500-1:2000 ICC/IF 1:50-1:200 FC 1:50 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 21A07 |
Immunogen | A synthesized peptide derived from human ATAD2 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | ATAD2 |
---|---|
Function | May be a transcriptional coactivator of the nuclear receptor ESR1 required to induce the expression of a subset of estradiol target genes, such as CCND1, MYC and E2F1. May play a role in the recruitment or occupancy of CREBBP at some ESR1 target gene promoters. May be required for histone hyperacetylation. Involved in the estrogen-induced cell proliferation and cell cycle progression of breast cancer cells. |
Cellular Location | Nucleus |
Tissue Location | Highly expressed in estrogen receptor positive breast tumors and in osteosarcoma tumors. |
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