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> home > Products > Primary Antibodies > Metabolism > Anti-Glutathione Peroxidase 2 Rabbit Monoclonal Antibody
Anti-Glutathione Peroxidase 2 Rabbit Monoclonal Antibody
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Application 
| WB, IHC |
|---|---|
| Primary Accession | P18283 |
| Host | Rabbit |
| Isotype | IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Glutathione Peroxidase 2 Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human. |
| Gene ID | 2877 |
|---|---|
| Other Names | Glutathione peroxidase 2, GPx-2, GSHPx-2, 1.11.1.9, Gastrointestinal glutathione peroxidase, Glutathione peroxidase-gastrointestinal, GPx-GI, GSHPx-GI, Glutathione peroxidase-related protein 2, GPRP-2, Phospholipid hydroperoxide glutathione peroxidase GPX2, 1.11.1.12, GPX2 {ECO:0000303|Ref.9, ECO:0000312|HGNC:HGNC:4554} |
| Calculated MW | 21954 Da |
| Application Details | WB 1:500-1:2000 IHC 1:50-1:200 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 20G43 |
| Immunogen | A synthesized peptide derived from human Glutathione Peroxidase 2 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | GPX2 {ECO:0000303|Ref.9, ECO:0000312|HGNC:HGNC:4554} |
|---|---|
| Function | Catalyzes the reduction of hydroperoxides in a glutathione- dependent manner thus regulating cellular redox homeostasis (PubMed:36608588, PubMed:8428933). Can reduce small soluble hydroperoxides such as H2O2, cumene hydroperoxide and tert-butyl hydroperoxide, as well as several fatty acid-derived hydroperoxides (PubMed:36608588, PubMed:8428933). Cannot reduce phosphatidycholine hydroperoxide (PubMed:8428933). |
| Cellular Location | Cytoplasm, cytosol. |
| Tissue Location | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO15467
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