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> home > Products > Primary Antibodies > Signal Transduction > Anti-MGEA5 Rabbit Monoclonal Antibody
Anti-MGEA5 Rabbit Monoclonal Antibody
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Application 
| WB, IHC, IP |
|---|---|
| Primary Accession | O60502 |
| Host | Rabbit |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-MGEA5 Rabbit Monoclonal Antibody . Tested in WB, IHC, IP applications. This antibody reacts with Human, Mouse. |
| Gene ID | 10724 |
|---|---|
| Other Names | Protein O-GlcNAcase {ECO:0000303|PubMed:11148210, ECO:0000303|PubMed:11788610, ECO:0000305}, OGA, 3.2.1.169, Beta-N-acetylglucosaminidase, Beta-N-acetylhexosaminidase, Beta-hexosaminidase, Meningioma-expressed antigen 5, N-acetyl-beta-D-glucosaminidase, N-acetyl-beta-glucosaminidase, Nuclear cytoplasmic O-GlcNAcase and acetyltransferase, NCOAT, OGA {ECO:0000303|PubMed:20863279, ECO:0000312|HGNC:HGNC:7056} |
| Calculated MW | 130 kDa |
| Application Details | WB 1:1000-1:5000 IHC 1:50-1:200 IP 1:80 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 20O25 |
| Immunogen | A synthesized peptide derived from human MGEA5 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | OGA {ECO:0000303|PubMed:20863279, ECO:0000312|HGNC:HGNC:7056} |
|---|---|
| Function | [Isoform 1]: Cleaves GlcNAc but not GalNAc from O- glycosylated proteins (PubMed:11148210, PubMed:11788610, PubMed:20673219, PubMed:22365600, PubMed:24088714, PubMed:28939839, PubMed:37962578). Deglycosylates a large and diverse number of proteins, such as CRYAB, ELK1, GSDMD, LMNB1 and TAB1 (PubMed:28939839, PubMed:37962578). Can use p-nitrophenyl-beta-GlcNAc and 4- methylumbelliferone-GlcNAc as substrates but not p-nitrophenyl-beta- GalNAc or p-nitrophenyl-alpha-GlcNAc (in vitro) (PubMed:20673219). Does not bind acetyl-CoA and does not have histone acetyltransferase activity (PubMed:24088714). |
| Cellular Location | [Isoform 3]: Nucleus |
| Tissue Location | Ubiquitous. Shows highest expression in the brain, placenta and pancreas. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO15449
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