Anti-Nectin 2 Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| WB, IF, ICC, IP, FC |
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Primary Accession | Q92692 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Rat, Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Nectin 2 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat. |
Gene ID | 5819 |
---|---|
Other Names | Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2 {ECO:0000312|HGNC:HGNC:9707}, Poliovirus receptor-related protein 2, CD112, NECTIN2 (HGNC:9707), HVEB, PRR2, PVRL2 |
Calculated MW | 62-75 kDa |
Application Details | WB 1:500-1:2000 ICC/IF 1:50-1:200 IP 1:100 FC 1:50 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 20N15 |
Immunogen | A synthesized peptide derived from human Nectin 2 |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | NECTIN2 (HGNC:9707) |
---|---|
Synonyms | HVEB, PRR2, PVRL2 |
Function | Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005). |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
Tissue Location | Ubiquitous. |

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