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Anti-Nectin 2 Rabbit Monoclonal Antibody

     
  •  - Anti-Nectin 2 Rabbit Monoclonal Antibody ABO15439
    Western blot analysis of Nectin 2 expression in SW480 cell lysate.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immuno electron microscopy
  • EIA=Enzyme Immunoassay
WB, IF, ICC, IP, FC
Primary Accession Q92692
Host Rabbit
Isotype IgG
Reactivity Rat, Human, Mouse
Clonality Monoclonal
Format Liquid
Description Anti-Nectin 2 Rabbit Monoclonal Antibody . Tested in WB, ICC/IF, IP, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.
Additional Information
Gene ID 5819
Other Names Nectin-2, Herpes virus entry mediator B, Herpesvirus entry mediator B, HveB, Nectin cell adhesion molecule 2 {ECO:0000312|HGNC:HGNC:9707}, Poliovirus receptor-related protein 2, CD112, NECTIN2 (HGNC:9707), HVEB, PRR2, PVRL2
Calculated MW 62-75 kDa
Application Details WB 1:500-1:2000
ICC/IF 1:50-1:200
IP 1:100
FC 1:50
Contents Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Clone Names Clone: 20N15
Immunogen A synthesized peptide derived from human Nectin 2
Purification Affinity-chromatography
Storage Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Information
Name NECTIN2 (HGNC:9707)
Synonyms HVEB, PRR2, PVRL2
Function Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive (PubMed:26755705). Probable cell adhesion protein (PubMed:9657005).
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Ubiquitous.
Research Areas
Citations (0)
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$ 370.00
Cat# ABO15439
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