Anti-Prostatic Acid Phosphatase Rabbit Monoclonal Antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, IHC, IF, ICC, IP |
---|---|
Primary Accession | P15309 |
Host | Rabbit |
Isotype | IgG |
Reactivity | Human, Mouse |
Clonality | Monoclonal |
Format | Liquid |
Description | Anti-Prostatic Acid Phosphatase Rabbit Monoclonal Antibody . Tested in WB, IHC, ICC/IF, IP applications. This antibody reacts with Human, Mouse. |
Gene ID | 55 |
---|---|
Other Names | Prostatic acid phosphatase, PAP, 3.1.3.2, 5'-nucleotidase, 5'-NT, 3.1.3.5, Ecto-5'-nucleotidase, Protein tyrosine phosphatase ACP3, 3.1.3.48, Thiamine monophosphatase, TMPase, PAPf39, ACP3 (HGNC:125), ACPP |
Calculated MW | 50 kDa |
Application Details | WB 1:500-1:2000 IHC 1:50-1:200 ICC/IF 1:50-1:200 IP 1:50 |
Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
Clone Names | Clone: 19A64 |
Immunogen | A synthesized peptide derived from human Prostatic Acid Phosphatase |
Purification | Affinity-chromatography |
Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
Name | ACP3 (HGNC:125) |
---|---|
Synonyms | ACPP |
Function | A non-specific tyrosine phosphatase that dephosphorylates a diverse number of substrates under acidic conditions (pH 4-6) including alkyl, aryl, and acyl orthophosphate monoesters and phosphorylated proteins (PubMed:10506173, PubMed:15280042, PubMed:20498373, PubMed:9584846). Has lipid phosphatase activity and inactivates lysophosphatidic acid in seminal plasma (PubMed:10506173, PubMed:15280042). |
Cellular Location | [Isoform 1]: Secreted |
Tissue Location | Highly expressed in the prostate, restricted to glandular and ductal epithelial cells. Also expressed in bladder, kidney, pancreas, lung, cervix, testis and ovary. Weak expression in a subset of pancreatic islet cells, squamous epithelia, the pilosebaceous unit, colonic neuroendocrine cells and skin adnexal structures. Low expression in prostate carcinoma cells and tissues |
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