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> home > Products > Primary Antibodies > Signal Transduction > Anti-Rab25 Rabbit Monoclonal Antibody
Anti-Rab25 Rabbit Monoclonal Antibody
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Application 
| WB |
|---|---|
| Primary Accession | P57735 |
| Host | Rabbit |
| Isotype | IgG |
| Reactivity | Human |
| Clonality | Monoclonal |
| Format | Liquid |
| Description | Anti-Rab25 Rabbit Monoclonal Antibody . Tested in WB application. This antibody reacts with Human. |
| Gene ID | 57111 |
|---|---|
| Other Names | Ras-related protein Rab-25, CATX-8, RAB25 (HGNC:18238), CATX8 |
| Calculated MW | 23496 Da |
| Application Details | WB 1:500-1:1000 |
| Contents | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA. |
| Clone Names | Clone: 19R29 |
| Immunogen | A synthesized peptide derived from human Rab25 |
| Purification | Affinity-chromatography |
| Storage | Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles. |
| Name | RAB25 (HGNC:18238) |
|---|---|
| Synonyms | CATX8 |
| Function | Involved in the regulation of cell survival. Promotes invasive migration of cells in which it functions to localize and maintain integrin alpha-V/beta-1 at the tips of extending pseudopodia (PubMed:17925226). Involved in the regulation of epithelial morphogenesis through the control of CLDN4 expression and localization at tight junctions (By similarity). May selectively regulate the apical recycling pathway. Together with MYO5B regulates transcytosis (By similarity). |
| Cellular Location | Cell membrane; Lipid-anchor; Cytoplasmic side. Cell projection, pseudopodium membrane. Cytoplasmic vesicle. Note=Colocalizes with integrin alpha-V/beta-1 in vesicles at the pseudopodial tips |
| Tissue Location | Expressed in ovarian epithelium (NOE) and breast tissue. Expressed in ovarian cancer; expression is increased relative to NOE cells. Expression in ovarian cancer is stage dependent, with stage III and stage IV showing higher levels than early stage cancers Expressed in breast cancer; expression is increased relative to normal breast tissue. |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
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$ 370.00
Cat# ABO15353
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